Abstract Receptor tyrosine kinases (RTKs), a category of transmembrane receptors, have gained significant clinical attention in oncology due to their central role in cancer pathogenesis.Genetic alterations, including mutations, amplifications, and overexpression of certain RTKs, are critical in creating environments conducive to tumor development.F
Diversification of Amazonian spiny tree rats in genus Makalata (Rodentia, Echimyidae): Cryptic diversity, geographic structure and drivers of speciation
Amazonian mammal diversity is exceptionally high, yet new taxonomic discoveries continue to be made and many questions remain for understanding its Chest diversification through time and space.Here we investigate the diversification of spiny rats in the genus Makalata, whose species are strongly associated with seasonally flooded forests, watercour
Structure Prediction of Outer Membrane Protease Protein of Salmonella typhimurium Using Computational Techniques
Salmonella typhimurium, a facultative gram-negative intracellular pathogen belonging to family Enterobacteriaceae, is the most frequent cause of human gastroenteritis worldwide.PgtE gene product, outer membrane protease emerges important in the intracellular phases of salmonellosis.The pgtE gene product Straighteners of S.typhimurium was predicted
Soft Gripper Design and Fabrication for Underwater Grasping
Underwater manipulation with current robotics technology is a Crevice Nozzle challenging task with significant limits in versatility and robustness terms.Such functionality has tremendous potential covering a broad spectrum of applications, mainly replacing divers performing hazardous jobs.Soft robotics provides an efficient solution for operating
LOW-FREQUENCY DYNAMIC CHARACTERISTICS OF A MECHANICAL VIBRATION SYSTEM UNDER BILATERAL NONLINEAR RESTRAINTS (MT)
A type of two-degree-of-freedom vibration system with bilateral nonlinear constraints is established.Through the fourth-order Runge-Kutta numerical algorithm, the dynamic characteristics of the p/1 periodic motion of the system under low frequency excitation, the law of mutual transition and the corresponding law of the coexistence zone of gap and